Thermo Fisher Scientific B-Myb Recombinant Superclonal Antibody (5HCLC)

Applications

Western Blot (WB)

• Tested Dilution: 2.5 µg/mL

Product Specifications

Product Specific Information

• Predicted to react with Monkey, Cat, Horse
• Recombinant rabbit Superclonal™ antibodies are composed of multiple different recombinant monoclonal antibodies.
• Provide the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies.
• Offer lot-to-lot consistency by eliminating biological variability.
• Previously marketed as “Recombinant Polyclonal Antibody”; now rebranded as “Recombinant Superclonal™ Antibody” with unchanged performance.

Target Information

Nucleocytoplasmic transport is a signal- and energy-dependent process mediated by nuclear pore complexes. Proteins containing a nuclear localization signal (NLS) require importin alpha and beta subunits (karyopherins) for nuclear import. Importin alpha binds NLS-containing cargo, while importin beta docks the complex at the nuclear pore. In the presence of nucleoside triphosphates and Ran GTPase, the complex translocates through the pore, after which importin alpha and beta dissociate. Importin alpha enters the nucleoplasm with cargo, and importin beta remains at the pore. Interactions between importin beta and nucleoporin FG repeats are essential for this process. The encoded protein belongs to the importin beta family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.