Thermo Fisher Scientific ELOA3 Polyclonal Antibody
ELOA3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 370–422 of Human Elongin A3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553459 |
Product Specific Information
- Detects endogenous ELOA3 protein at approximately 60 kDa.
- Purity >95% by SDS-PAGE.
Target Information
The Elongin (SIII) complex consists of a transcriptionally active A subunit and two small regulatory subunits, B and C. This complex enhances the transcription elongation rate of RNA polymerase II by reducing pausing at DNA arrest sites.
Elongin A3, also known as RNA polymerase II transcription factor SIII subunit A3 or Transcription elongation factor B polypeptide 3C, is a 546 amino acid nuclear protein functioning as a general transcription elongation factor. It forms a stable complex with Elongin BC and increases RNA polymerase II transcription elongation. Unlike Elongin A, Elongin A3 activity is not stimulated by Elongin BC. Elongin A3 contains one TFIIS N-terminal domain and is ubiquitously expressed in human tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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