Thermo Fisher Scientific Laminin gamma-1 Polyclonal Antibody
Laminin gamma-1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관됩니다. 세포외기질 연구 및 basement membrane 분석에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | – |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1441–1490 of human Laminin gamma-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS (pH 7.2) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553460 |
Product Specific Information
- Detects endogenous Laminin gamma-1 protein at ~178 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Laminins are essential structural non-collagenous glycoproteins localized to basement membranes. These membranes, composed of Laminins, Type IV Collagen, Nidogen, and proteoglycans, are found under epithelial layers, around blood vessels, and surrounding muscle, nerve, and fat cells. Laminins influence cell proliferation, migration, gene expression, and tissue architecture. Each Laminin is a heterotrimer of alpha, beta, and gamma chains that assemble into the extracellular matrix and interact with integrins, dystroglycan, and other receptors. The human Laminin gamma-1 gene (chromosome 1q31) is widely expressed in basement membrane-producing tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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