Thermo Fisher Scientific ITFG2 Monoclonal Antibody (OTI 3D8), TrueMAB
Thermo Fisher Scientific의 ITFG2 단클론 항체(OTI 3D8)는 인간 ITFG2 단백질을 인식하는 Mouse IgG1 항체입니다. Western blot과 유세포분석에 사용 가능하며, 고순도 친화 크로마토그래피 정제 제품입니다. 동결건조 형태로 제공되며 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI 3D8 |
| Immunogen | Full length human recombinant protein of human ITFG2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ITFG2 is a component of the KICSTOR complex, functioning in the amino acid-sensing branch of the TORC1 signaling pathway. It recruits the GATOR1 complex to lysosomal membranes, enabling interaction with GATOR2 and RAG GTPases. ITFG2 negatively regulates mTORC1 signaling in the absence of amino acids and may also be involved in mTORC1 regulation by glucose.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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