Thermo Fisher Scientific P2X1 Polyclonal Antibody
P2X1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 IHC에 적합합니다. 인간, 마우스, 설치류, 영장류에 반응하며, ATP 수용체 연구에 유용합니다. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (IHC) | 1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the cytoplasmic domain of human P2X1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen shares 92% identity with rat and mouse sequence.
- Specificity: P2RX1.
Target Information
The product of this gene belongs to the family of purinoceptors for ATP.
This receptor functions as a ligand-gated ion channel with relatively high calcium permeability.
Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, playing a role in sympathetic vasoconstriction in small arteries, arterioles, and vas deferens.
Mouse studies suggest that this receptor is essential for normal male reproductive function.
Development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive approach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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