Thermo Fisher Scientific P2RX3 Polyclonal Antibody
Thermo Fisher Scientific의 P2RX3 Polyclonal Antibody는 인간 P2X3 수용체를 인식하는 토끼 유래 항체입니다. Western blot 및 IHC에 적합하며, 통증 및 요로 반사 관련 연구에 활용됩니다. 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the cytoplasmic domain of human P2X3 (P2RX3, P2X purinoceptor 3, ATP receptor) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide shares 85% identity with rat and mouse sequences.
- Specificity: P2RX3.
Target Information
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses and participates in pathways controlling urinary bladder volume reflexes. Selective antagonists for this receptor may have therapeutic potential in pain relief and treatment of urinary storage disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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