Thermo Fisher Scientific MEK1 Recombinant Rabbit Monoclonal Antibody (BLR095G)
MEK1 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, Flow cytometry, Immunoprecipitation에 적합합니다. 인간 및 생쥐 시료 반응성이 있으며, HEK293 세포에서 발현된 정제 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Usage |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 2 µL per 1 × 10⁶ cells |
| Immunoprecipitation (IP) | 20 µL / 1 mg lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR095G |
| Immunogen | Peptide representing a region between residues 1 and 50 of human dual specificity mitogen-activated protein kinase kinase 1 (MEK1). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 7.8–8.6, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx. MEK1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is involved in signaling during stress-activated response, apoptosis, and proliferative induction by cytokines. Mutations in the gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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