Thermo Fisher Scientific MEK1/MEK2 Recombinant Rabbit Monoclonal Antibody (SR13-07)
MEK1/MEK2 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, IHC, ICC/IF에 적합. 높은 특이성과 민감도, 로트 간 일관성 및 동물 유래 성분 무첨가. 연구용으로 세포 성장 및 신호전달 경로 분석에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SR13-07 |
| Immunogen | Recombinant protein within Human MEK1 aa 1–393 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809292 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal clones for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is a key component of the MAP kinase cascade regulating cell growth and differentiation. In the brain, this pathway plays a crucial role in synaptic signaling. Activated MEK1 functions as a dual-specificity kinase, phosphorylating both threonine and tyrosine residues on MAP kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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