Thermo Fisher Scientific C5AR1 Monoclonal Antibody (S5/1), FITC
인간 C5a 수용체(CD88)를 인식하는 단클론 항체로, FITC 형광 표지되어 유세포 분석에 적합합니다. 단백질 A로 정제되었으며, PBS + 1% BSA 용액에 보관됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific C5AR1 Monoclonal Antibody (S5/1), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S5/1 |
| Immunogen | C5aR peptide: Met1–Asn31 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; -20°C long term (avoid freeze/thaw). Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745079 |
Product Specific Information
Mouse anti-Human CD88 antibody, clone S5/1, recognizes the C5a receptor (C5aR, CD88), predominantly expressed on myeloid lineage cells.
Target Information
CD88 (C5aR1) is a C5a Anaphylatoxin Receptor mediating effects of a potent chemotactic agent. It is expressed in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract.
Functionally, CD88 stimulates chemotaxis, granule enzyme release, and superoxide anion production. It is part of the classical complement pathway and may contribute to tissue injury associated with ischemia or sepsis.
Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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