Thermo Fisher Scientific CD6 Monoclonal Antibody (MEM-98), FITC
인간 CD6 항원을 인식하는 Mouse IgG1 단클론 항체로 FITC 형광 표지. Flow Cytometry에 적합하며, 498/517 nm에서 여기/방출. PBS + 1% BSA 버퍼에 0.09% sodium azide 포함. 4°C 단기 보관, 장기 보관 시 -20°C.
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Applications
- Flow Cytometry (Flow)
Tested Dilution
- Neat
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-98 |
| Immunogen | Purified CD6 antigen |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745084 |
Product Specific Information
Mouse anti Human CD6 antibody, clone MEM-98 recognizes human CD6, also known as T12 or TP120.
Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL).
CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse.
CD6-ALCAM mediated cell adhesion is also important for T cell proliferation.
CD6 may exert some of its functions via association with CD5, probably by fine-tuning CD5 signaling.
Ligation of CD6 has an antiapoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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