Thermo Fisher Scientific ALDH7A1 Recombinant Rabbit Monoclonal Antibody (105)
인간 ALDH7A1 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot, ELISA, IP에 적합하며 높은 특이성과 재현성을 제공. 보존제 무첨가로 세포배양 유래 단백질 A 정제. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 105 |
| Immunogen | Recombinant Human ALDH7A1 protein (Ser2–Gln511) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2784967 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in HEK293 cells. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Human ALDH7A1.
Target Information
The protein encoded by the ALDH7A1 gene belongs to the aldehyde dehydrogenase family (subfamily 7). These enzymes are involved in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation.
This protein participates in lysine catabolism in the mitochondrial matrix and is found in both the cytosol and mitochondria due to alternative translation initiation sites.
Mutations in this gene are associated with pyridoxine-dependent epilepsy, and several pseudogenes have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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