Thermo Fisher Scientific Phospho-eNOS (Thr495) Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Positive test controls include NIH/3T3 cells.
The target is typically localized in the cell membrane, cytoplasm, Golgi apparatus, membrane caveola, and cytoskeleton.

Immunogen sequence: KKTFK

Target Information

Nitric oxide (NO) is an inorganic, gaseous free radical that mediates various intercellular signals such as vasorelaxation, neurotransmission, and cytotoxicity.
NO production is catalyzed by nitric oxide synthase (NOS) enzymes, which oxidize L-arginine to L-citrulline and NO.
There are three NOS isoforms:

• Neuronal NOS (nNOS, type I)
• Endothelial NOS (eNOS, type III)
• Inducible NOS (iNOS, type II)

All NOS isoforms contain calmodulin, NADPH, FAD, and FMN binding domains.

주의사항

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.