Thermo Fisher Scientific Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:100–1:500

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Positive test controls include: HeLa
• Immunogen sequence: TDYYRV

Target Information

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes.
Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: PA5-121285_TrkATrkB_P04629-1_Rabbit.svg, PA5-121285_TrkATrkB_P04629-1_Rabbit_PDP.jpeg)