
Thermo Fisher Scientific AXUD1 Polyclonal Antibody
인간 AXUD1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. 합성 펩타이드(aa 173-186)를 면역원으로 사용. 1 mg/mL 농도의 액상 형태이며, 항원 친화 크로마토그래피로 정제됨. -20°C 보관, 동결-해동 반복은 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide: D(173)AIDDA SVEE DLAV(186) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_557682 |
Product Specific Information
- PA1-4275 detects the AXUD1 protein in human samples.
- Successfully used in Western blot procedures.
- Immunogen corresponds to amino acid residues 173–186 of the human AXUD1 protein.
Target Information
Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs). Transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC and colon cancer cells.
A novel gene, AXUD1 (AXIN1 up-regulated), shows enhanced expression in response to exogenously expressed AXIN1. It is expressed in all human tissues examined, with highest levels in lung, placenta, skeletal muscle, pancreas, and leukocytes.
Data suggests that AXUD1 may have a tumor-suppressor function in these organs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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