Thermo Fisher Scientific NDUFA13 Polyclonal Antibody
Human, Mouse, Rat에서 GRIM-19 단백질을 검출하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 합성 펩타이드 면역원 기반, 액상 형태로 1 mg/mL 농도. 냉장 또는 장기 보관 시 -20°C에서 안정적.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide: Q(159) A E T D R R T L Q M L R E(172) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2150605 |
Product Specific Information
PA1-4272 detects the GRIM-19 protein in human, mouse, and rat samples.
It has been successfully used in Western blot procedures.
The immunizing peptide corresponds to amino acid residues 159–172 of the human GRIM-19 protein.
Target Information
A novel gene associated with Retinoid-IFN-induced Mortality (GRIM), GRIM-19, was identified.
Antisense expression of GRIM-19 confers strong resistance against IFN/RA-induced death by reducing intracellular GRIM-19 protein levels.
Overexpression of GRIM-19 enhances cell death in response to IFN/RA.
GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination, indicating that GRIM-19 is a novel cell death-regulatory molecule.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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