Thermo Fisher Scientific DCBLD2 Polyclonal Antibody
Rabbit polyclonal antibody against DCBLD2 for human, mouse, and rat samples. Validated for Western blot (1:500 dilution). Antigen affinity purified and supplied in PBS with sodium azide. Ideal for research use only; store at -20°C.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: Q(399) D K I F Q G N K D Y H K D V R N N(416) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2089741 |
Product Specific Information
- PA1-4270 detects ESDN from human, mouse, and rat samples.
- Successfully used in Western blot procedures.
- Immunizing peptide corresponds to amino acid residues 399–416 from mouse and rat ESDN protein.
Target Information
This protein is a key enzyme in the catabolic pathway of odd-chain fatty acids, isoleucine, threonine, methionine, and valine. It is probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. The protein is located in the mitochondrial matrix. Defects in PCCA are the cause of propionic acidemia type I (PA-1) [MIM:606054]. PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy, ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(PA1-4270_DCBLD2_Q96PD2-1_Rabbit.svg, PA1-4270_DCBLD2_Q96PD2-1_Rabbit_PDP.jpeg)
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