Thermo Fisher Scientific Fibronectin Monoclonal Antibody (FN1/3045)
인체 유래 섬유소단백질(Fibronectin)을 인식하는 마우스 단클론 항체로, IHC, ELISA, Peptide Array 등에 사용 가능. 단백질 A/G로 정제된 액상 포맷이며, PBS(pH 7.4) 내 보존제 없이 제공. -20°C 보관, 동결/해동 반복은 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FN1/3045 |
| Immunogen | Recombinant fragment (around aa 467–595) of human fibronectin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Fibronectin is a disulfide-bonded dimer with a molecular weight range of 230–250 kDa. In the extracellular matrix of connective tissues and vessels, it exists as an insoluble, cross-linked protein forming high molecular mass polymers. Fibronectin plays key roles in cell adhesion, migration, embryogenesis, wound healing, blood coagulation, host defense, and metastasis. It is abundantly expressed during tissue remodeling and development, and its expression is elevated in non-small cell lung carcinoma. The gene encoding fibronectin undergoes alternative splicing, producing up to 20 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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