Thermo Fisher Scientific CD298 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 5 µg/mL

Product Specifications

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Monkey (100%), Gibbon (94%).

Target Information

The protein encoded by this gene belongs to the family of Na⁺/K⁺ and H⁺/K⁺ ATPases beta chain proteins, and to the subfamily of Na⁺/K⁺-ATPases.
Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane.
These gradients are essential for osmoregulation, sodium-coupled transport of various molecules, and electrical excitability of nerve and muscle.
The enzyme consists of two subunits: a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates the number of sodium pumps transported to the plasma membrane through assembly of alpha/beta heterodimers.
The glycoprotein subunit of Na⁺/K⁺-ATPase is encoded by multiple genes, and this gene encodes a beta 3 subunit. A pseudogene exists for this gene on chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.