Thermo Fisher Scientific CD298 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Percent identity with other species by BLAST analysis:
Human, Gibbon, Monkey, Marmoset (100%)
Guinea pig (94%)
Rabbit, Lizard (88%)

Target Information

The protein encoded by this gene belongs to the family of Na⁺/K⁺ and H⁺/K⁺ ATPases beta chain proteins, and to the subfamily of Na⁺/K⁺ -ATPases.
Na⁺/K⁺ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane.
These gradients are essential for osmoregulation, sodium-coupled transport of various organic and inorganic molecules, and electrical excitability of nerve and muscle.
This enzyme is composed of two subunits: a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta).
The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
The glycoprotein subunit of Na⁺/K⁺ -ATPase is encoded by multiple genes, and this gene encodes the beta 3 subunit.
A pseudogene exists for this gene, located on chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.