Thermo Fisher Scientific Angiotensinogen Polyclonal Antibody
인간 및 비인간 영장류에 반응하는 Angiotensinogen 폴리클로날 항체입니다. IHC 및 파라핀 포매 조직에서 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 혈압 조절 관련 단백질 연구에 적합하며, 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: -
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2.5–5 µg/mL
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 13 amino acid peptide from internal region of human AGT / Angiotensinogen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550721 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset (85%).
Target Information
The AGT gene encodes pre-angiotensinogen (angiotensinogen precursor), primarily expressed in the liver. It is cleaved by renin in response to low blood pressure to form angiotensin I, which is further processed by angiotensin converting enzyme (ACE) into angiotensin II, an active regulator of blood pressure.
This protein is involved in maintaining blood pressure and is linked to essential hypertension and preeclampsia. Mutations can cause renal tubular dysgenesis and are associated with structural atrial fibrillation and inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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