Thermo Fisher Scientific c-Myc Monoclonal Antibody (9E10), HRP
HRP 결합형 c-Myc 단클론 항체(클론 9E10)로 인간 및 태그 단백질 검출에 적합. Western blot 등 다양한 응용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific c-Myc Monoclonal Antibody (9E10), HRP
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:250–1:1,000 | View 4 publications |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Flow Cytometry (Flow) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Tag |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9E10 |
| Immunogen | Synthetic peptide A(408) E E Q K L I S E E D L L R K R R E Q L K H K L E Q L R N S C A(438) of human c-Myc |
| Conjugate | HRP |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | Proprietary buffer with proprietary stabilizer |
| Contains | 0.07% Kathon |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2537628 |
Additional Formats
- Unconjugated
- Alexa Fluor 488
- Alexa Fluor 555
- Alexa Fluor 647
- DyLight 488
- FITC
- Request custom conjugation
Product Specific Information
MA1-980-HRP detects c-Myc protein and c-Myc tagged proteins.
It has been successfully used in Western blot procedures.
The immunogen corresponds to the synthetic peptide A(408)–A(438) of human c-Myc.
Target Information
The c-Myc protein is a 62 kDa transcription factor encoded by the c-Myc gene on human chromosome 8q24.
It is commonly activated in various tumor cells and plays a key role in cellular proliferation, differentiation, apoptosis, and cell cycle progression.
Phosphorylation at Thr58/Ser62 by kinases such as GSK3, CDK, ERK2, and JNK is associated with regulation of cell proliferation and cycle control.
c-Myc is essential for vasculogenesis and angiogenesis in tumor development.
Antibodies against c-Myc epitopes recognize overexpressed proteins containing Myc epitope tags fused to either amino- or carboxy-termini of target proteins.
Amplification or translocation of the c-Myc gene has been found in several human tumors including lung, breast, and colon carcinomas, as well as in Burkitt’s lymphoma and other B-cell lymphoproliferative diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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