Thermo Fisher Scientific Cystatin 2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Cystatin 2 for WB applications. High purity (>95%) by affinity chromatography. Unconjugated liquid form with 1 mg/mL concentration. Suitable for human and mouse samples; research use only.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human Cystatin 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719829 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using epitope-specific immunogen. Purity >95% by SDS-PAGE.
Target Information
The cystatin superfamily comprises cysteine protease inhibitors.
- Type 1 (Cystatins A, B): Mainly intracellular
- Type 2 (Cystatins C, D, E/M, F, G, S, SN, SA): Extracellular
- Type 3 (Kininogens): Intravascular proteins
All true cystatins inhibit papain family cysteine peptidases (e.g., cathepsins) and some also inhibit legumain family enzymes.
Cystatin SA, S, and SN are found primarily in saliva and also expressed in tears, urine, and seminal fluid.
Cystatin C is expressed in brain, thymus, ovary, epididymis, and vas deferens.
Cystatin D protects against oral cavity proteinases, while Cystatin E/M and F moderate cathepsin inhibition.
Fetuins, part of the cystatin superfamily, influence osteogenesis, bone resorption, insulin receptor regulation, and inflammatory responses.
High and low molecular weight kininogens inhibit thrombin- and plasmin-induced thrombocyte aggregation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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