Thermo Fisher Scientific Progestin Receptor beta Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: Assay-dependent

Immunocytochemistry (ICC/IF)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

PA3-881 detects progestin receptor beta in mouse, rat, human, and porcine cells.
It has been successfully used in Western blotting and immunofluorescence procedures.
By Western blot, it detects a 40 kDa protein representing PR beta.
The immunogen is a protein-specific peptide sequence conjugated to KLH, recognizing extracellular epitopes.

Target Information

Progestin Receptor Beta recognizes the extracellular epitope of the membrane progestin receptor.
Progestin receptors are found in pituitary, reproductive tract, and most estrogen receptor-containing brain regions; these receptors are inducible by estrogen treatment.
There are also progestin receptor sites in brain areas lacking estrogen receptors, such as the cerebral cortex of the rat; these receptors are not induced by estradiol treatment but resemble those induced by estradiol.
Testosterone can also induce progestin receptors through its conversion to estradiol via aromatization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.