Thermo Fisher Scientific beta-Phosphoglucomutase Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• For extended storage, aliquot contents and freeze at -20°C or below.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.

Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-goat serum, purified and partially purified beta-Phosphoglucomutase (Lactococcus lacti).
Cross-reactivity against beta-Phosphoglucomutase from other sources is unknown.

Target Information

Beta-Phosphoglucomutase catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), forming beta-D-glucose 1,6-(bis)phosphate (beta-G16P) as an intermediate.
The enzyme acts on the beta-C1 anomer of G1P and plays a key role in regulating carbohydrate intermediates in glycolysis and UDP-glucose formation.
Catalysis proceeds via a phosphoenzyme formed by reaction of an active-site nucleophile with the cofactor glucose 1,6-diphosphate (G1,6-diP).
The phosphorylated mutase binds either G1P or G6P and transfers the phosphoryl group to C6OH or C1OH, respectively.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.