
Thermo Fisher Scientific CARD11 Polyclonal Antibody
CARD11 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제된 액상 제품이며, 1 mg/mL 농도. NF-kappaB 신호전달 연구에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (IHC) | 10 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154116 |
Product Specific Information
- In Western blot applications, this antibody detects a band at approximately 125 kDa.
- A suggested positive control is mouse thymus tissue lysate.
- PA5-20032 can be used with blocking peptide PEP-0151.
Target Information
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, functioning as a molecular scaffold for multiprotein complex assembly at specialized plasma membrane regions. It is also a member of the CARD protein family, characterized by a caspase-associated recruitment domain (CARD).
This protein shares domain structure similarity with CARD14 and interacts specifically with BCL10, a positive regulator of cell apoptosis and NF-kappaB activation. Expression of this protein activates NF-kappaB and induces phosphorylation of BCL10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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