Thermo Fisher Scientific Bcl-B Monoclonal Antibody (8A11G12)
Bcl-B 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, Flow cytometry, ELISA에 적합. 인간 시료에 반응하며, Protein G로 정제된 액상형 제품. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8A11G12 |
| Immunogen | Purified recombinant fragment of human BCL2L10 (AA: 31–186) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787272 |
Product Specific Information
MA5-31648 has been tested in indirect ELISA.
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities.
This protein contains conserved BH4, BH1, and BH2 domains and can interact with other BCL-2 family members including BCL2, BCL2L1/BCL-X(L), and BAX.
Overexpression of this gene suppresses cell apoptosis, possibly by preventing cytochrome C release from mitochondria and inhibiting caspase-3 activation.
The mouse counterpart interacts with Apaf1 and forms a complex with Caspase 9, suggesting involvement in the APAF1–CASPASE 9 apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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