Thermo Fisher Scientific Bcl-B Monoclonal Antibody (8A2F9)
인간 Bcl-B 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 8A2F9). Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 적합. 고순도 Protein G 정제, 1 mg/mL 농도, PBS buffer 및 sodium azide 함유. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8A2F9 |
| Immunogen | Purified recombinant fragment of human BCL2L10 (AA: 31–186) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787271 |
Product Specific Information
MA5-31647 has been tested in indirect ELISA.
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as regulators of apoptosis, either promoting or inhibiting cell death.
This protein contains conserved BH4, BH1, and BH2 domains, and interacts with other BCL-2 family members including BCL2, BCL2L1/BCL-X(L), and BAX.
Overexpression may suppress cell apoptosis by preventing cytochrome C release from mitochondria and inhibiting caspase-3 activation.
In mouse, this protein interacts with Apaf1 and forms a complex with Caspase 9, suggesting involvement in APAF1 and CASPASE 9-related apoptotic pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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