Thermo Fisher Scientific TdT/DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Recombinant Rabbit Monoclonal Antibody (DNTT/4617R)
Recombinant rabbit monoclonal antibody recognizing human TdT, a key marker for acute lymphoblastic leukemia. Suitable for IHC on paraffin and PFA-fixed tissues. High purity (Protein A/G), liquid form, 200 µg/mL concentration. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | DNTT/4617R |
| Immunogen | Recombinant fragment (around aa 52–192) of human DNTT protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus that catalyzes the polymerization of deoxynucleotides at the 3′ hydroxyl ends of oligo or polydeoxynucleotide initiators, functioning without a template.
TdT is a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leukemia. Determination of TdT expression is particularly valuable for differentiating lymphoblastic lymphoma from Burkitt’s lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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