Thermo Fisher Scientific TdT/DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Recombinant Rabbit Monoclonal Antibody (DNTT/4617R)
Acute Lymphoblastic Leukemia 진단 마커로 사용되는 TdT 단백질을 인식하는 Rabbit Recombinant Monoclonal 항체. IHC(P), IHC(PFA)에서 사용 가능하며, HEK293 세포 발현. 단백질 A/G 정제, 보존제 무첨가 PBS 용액 형태.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | DNTT/4617R |
| Immunogen | Recombinant fragment (around aa 52–192) of human DNTT protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus that catalyzes the polymerization of deoxynucleotides at the 3′ hydroxyl ends of oligo- or polydeoxynucleotide initiators and functions without a template. TdT is considered a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leukemia. Determining TdT expression is particularly useful in differentiating lymphoblastic lymphoma from Burkitt’s lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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