Thermo Fisher Scientific Phospho-FGFR1 (Tyr766) Polyclonal Antibody
Human FGFR1 (phospho Tyr766) 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 20% 글리세롤과 1% BSA 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide corresponding to residues around human FGFR1 (phospho Tyr766). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2902022 |
Product Specific Information
- Centrifuge briefly prior to opening.
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family (FGFR1–4), which serve as high-affinity receptors for 17 growth factors (FGF1–17).
The FGF receptor family plays a crucial role in biological processes such as mesoderm induction, patterning, cell growth, migration, organ formation, and bone development.
FGFR1 undergoes alternative splicing, generating multiple variants expressed differently during embryonic development and in adult tissues.
Defects in FGFR1 are linked to several disorders including Pfeiffer syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome type 2, osteoglophonic dysplasia, non-syndromic trigonocephaly, Jackson-Weiss syndrome, and Antley-Bixler syndrome.
Chromosomal aberrations involving FGFR1 are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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