Thermo Fisher Scientific FOXC1 Polyclonal Antibody
FOXC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에서 검증됨. Western blot, ICC/IF, ChIP assay에 사용 가능. 합성 펩타이드 기반 면역원으로 제작되었으며, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | View 3 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
| ChIP assay (ChIP) | 1–3 µg × 10⁶ cells | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues A(423) V D D P L P D Y S L P(434) of human FOXC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2247078 |
Product Specific Information
PA1-807 detects FOXC1 from human and mouse samples.
It has been successfully used in Western blot procedures.
By Western blot, PA1-807 detects a ~50 kDa band representing FOXC1 from HepG2 cells and mouse kidney cells.
This antibody also detects a nonspecific band at ~45 kDa from HepG2 cells, and at ~60 kDa from mouse kidney samples.
The immunogen is a synthetic peptide corresponding to residues A(423) V D D P L P D Y S L P(434) of human FOXC1.
PA1-807 can be used with blocking peptide PEP-298.
Target Information
FOXC1 is a protein belonging to the forkhead family of transcription factors characterized by a distinct DNA-binding forkhead domain.
It plays a role in regulating the FGF19–FGFR4–MAPK pathway, promoting the development and maintenance of anterior segment structures within the eye.
Mutations in this gene are associated with various ocular disorders such as glaucoma, iridogoniodysgenesis anomaly, Peters anomaly, and Axenfeld-Rieger anomaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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