Thermo Fisher Scientific PNR Polyclonal Antibody
Thermo Fisher Scientific의 PNR 폴리클로날 항체로, 인간 및 랫트 시료에서 PNR 단백질 검출에 적합합니다. Western blot에 최적화되어 있으며, 42 kDa 단백질을 식별합니다. 합성 펩타이드 기반 면역원 사용, -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2155474 |
Product Specific Information
- PA1-809 detects PNR from rat and human samples.
- Successfully used in Western blot procedures.
- Detects an ~42 kDa protein representing PNR from rat tissue extracts.
- Immunogen sequence is conserved between mouse and chicken.
- The immunizing peptide (cat. # PEP-237) can be used for neutralization and control experiments.
Target Information
NR2E3, a NR2 Hepatocyte NF4-Like Receptor, influences cone cell proliferation in eye development and photoreceptor phenotype during retinogenesis.
Mutations in NR2E3 are associated with hereditary retinal dysplasia, degeneration, and retinitis pigmentosa.
Two alternatively spliced isoforms have been documented.
NR2E3 is expressed in the retina, and ESTs have been isolated from human lung, colon, ovary (cancerous), and normal eye tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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