Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI2C9), TrueMAB
TMEM173(STING) 단백질을 인식하는 Mouse monoclonal antibody(OTI2C9). Western blot 및 Flow Cytometry에 적합하며, Lyophilized 형태로 제공. 인간 시료에 반응하며, 고순도의 affinity chromatography 정제 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C9 |
| Immunogen | Full length human recombinant protein of human TMEM173 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
STING (TMEM173) is a 379 amino acid signaling protein involved in innate immune signaling. It activates NF-κB and IRF3 transcription pathways to induce type I interferons (IFN-α, IFN-β), establishing an antiviral state.
STING may also have translocon function, influencing type I interferon induction and apoptotic signal transduction via MHC-II association. It is localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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