Thermo Fisher Scientific CD4 Monoclonal Antibody (2-35)
닭 CD4 항원을 인식하는 단클론 항체로 면역조직화학, 유세포분석, 면역침강 실험에 적합. Mouse IgG2b 아이소타입이며 비접합 형태로 제공. Protein G 정제, 1 mg/mL 농도, PBS 버퍼 및 sodium azide 함유. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- MA528359
- 판매단위
- pk
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2-35 |
| Immunogen | Chicken embryonic thymocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745322 |
Additional Formats
Product Specific Information
This antibody recognizes the chicken homologue of human CD4, approximately a 64 kDa cell surface protein expressed by thymocytes and a subset of T cells.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells, but also found in monocytes, macrophages, and dendritic cells. It is detectable in thymus, lymph nodes, tonsils, spleen, and certain regions of brain and gut. CD4 contributes to early T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck, and may mediate neuronal damage in infectious or immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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