Thermo Fisher Scientific Fibrinogen Monoclonal Antibody (UC45)
인간 피브리노겐 알파 체인에 강하게 반응하는 단클론 항체. Western blot, IHC(F), ICC/IF, RIA 등 다양한 응용에 사용 가능. 마우스 IgM 형식의 비결합 항체로, 1 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Radioimmune Assays (RIA) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UC45 |
| Immunogen | Human acute monoblastic leukemia cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_780633 |
Product Specific Information
MA1-26074 reacts very strongly with the alpha chain of human fibrinogen.
Target Information
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the major component of blood clots. Fibrinogen consists of a dimer of three pairs of non-identical chains (FGA, FGB, and FGG) cross-linked by disulfide bonds in their N-terminal segments. The molecule has two terminal D domains and one central E domain, which are separated when fibrinogen is degraded by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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