Thermo Fisher Scientific FceR1 alpha Recombinant Mouse Monoclonal Antibody (IE7)
인간 FcεR1 알파 수용체를 인식하는 재조합 마우스 단클론 항체로, IgE 결합과 경쟁하지 않음. HEK293 세포에서 발현되었으며 Protein A로 정제됨. Flow Cytometry 등 다양한 연구용 응용에 적합. 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific FceR1 alpha Recombinant Mouse Monoclonal Antibody (IE7)
Applications
- Flow Cytometry (Flow)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | IE7 |
| Immunogen | Recombinant human protein, N-terminus |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074676 |
Product Specific Information
Specificity: This antibody binds to human Fc epsilon receptor, but does not compete with IgE binding.
Target Information
FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is part of a tetrameric complex consisting of one alpha, one beta, and two additional subunits required for signal transduction.
This receptor plays a key role in triggering allergic responses. When allergen-bound IgE molecules cross-link FcεR1, mediators such as histamine are released, initiating inflammatory responses characteristic of allergic disorders like hay fever and asthma. The release of histamine and proteases also induces synthesis of prostaglandins and leukotrienes, potent effectors of hypersensitivity reactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-48233_FceR1_alpha_P12319-1_House_mouse.svg)
(이미지 파일명: MA5-48233_FceR1_alpha_P12319-1_House_mouse_PDP.jpeg)
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