Thermo Fisher Scientific TPCN2 Polyclonal Antibody, FITC
TPCN2 단백질을 인식하는 FITC 결합 토끼 폴리클로날 항체. Western blot, ELISA, 면역침강 등에 사용 가능. 사람 시료 반응성. 형광 검출용으로 적합하며, -20°C 암소 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 205–255 on human TPC2 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TPCN2 (Two-Pore Channel 2) is a nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca²⁺ channels across the lysosomal membrane. It is involved in smooth muscle contraction and encodes a cation-selective ion channel with two six-transmembrane-domain repeats. TPCN2 localizes to lysosomal membranes and mediates NAADP-induced calcium release from lysosome-related stores. The gene is ubiquitously expressed, with elevated expression in liver and kidney. Variants in TPCN2 are associated with differences in hair pigmentation and certain forms of autosomal recessive deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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