
Thermo Fisher Scientific TPCN2 Polyclonal Antibody
TPCN2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, ELISA, IP에 사용 가능. 합성 펩타이드(aa 205-255)를 면역원으로 제작. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관. 연구용으로만 사용.
- 카탈로그번호
- TPC2-212AP
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 205–255 on human TPC2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TPCN2 is a nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may act as a major voltage-gated Ca²⁺ channel across the lysosomal membrane. It is involved in smooth muscle contraction and encodes a cation-selective ion channel with two repeats of six transmembrane domains. The protein localizes to lysosomal membranes and mediates NAADP-induced calcium release from lysosome-related stores. TPCN2 is expressed ubiquitously, with higher expression in liver and kidney. Variants in TPCN2 are associated with traits such as hair pigmentation and certain forms of autosomal recessive deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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