Thermo Fisher Scientific AEG1 Polyclonal Antibody
Human 및 Mouse 반응성을 가진 Rabbit Polyclonal AEG1 항체. Western blot과 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. Metadherin 단백질 연구용으로 사용. 4°C 보관, 연구용 한정.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300 and 350 of human Astrocyte Elevated Gene-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Metadherin (Metastasis adhesion protein), also known as MTDH or LYRIC, is a protein that localizes with tight junction proteins ZO-1 and occludin in polarized epithelial cells. It is recruited during tight junction complex maturation rather than acting as a structural component. Metadherin is overexpressed in breast cancer tissues and xenografts, with lower levels in normal breast tissue. It binds to lung vasculature through a C-terminal segment in the extracellular domain, and inhibition of this interaction has been reported to reduce breast cancer metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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