Thermo Fisher Scientific CD314 (NKG2D) Monoclonal Antibody (CX5), Alexa Fluor 488, eBioscience

Applications and Tested Dilution

• Application: Flow Cytometry (Flow)
• Tested Dilution: 0.25 µg/test
• Publications: View 6 publications

Product Specifications

Additional Available Formats

• APC
• Functional Grade
• PE
• PE-Cyanine7
• PE-eFluor 610
• PerCP-eFluor 710
• Super Bright 436
• Super Bright 600
• Request custom conjugation

Product Specific Information

Description:
The CX5 monoclonal antibody reacts with mouse NKG2D, a lectin-like molecule expressed on both human and mouse NK cells. Mouse NKG2D binds to retinoic acid-inducible RAE-1 alpha, beta, gamma, delta, epsilon and the minor histocompatibility molecule H60, and can costimulate multiple NK activation receptors through DAP12/DAP10 adaptor molecules. NKG2D is expressed by spleen and liver NK cells, NK1.1⁺ thymocytes, in vitro activated LAK cells, and a subset of splenic NKT cells.

Applications Reported:
This CX5 antibody has been reported for use in flow cytometric analysis.

Applications Tested:
Tested by flow cytometric analysis of mouse splenocytes. Recommended ≤0.25 µg/test (defined as the amount of antibody for staining a cell sample in 100 µL). Optimal titration is recommended for best performance.

Excitation: 488 nm
Emission: 519 nm
Laser: Blue Laser

Target Information

Natural killer (NK) cells are lymphocytes capable of lysing tumor and virus-infected cells without prior activation. They regulate humoral and cell-mediated immunity and express C-type lectins involved in NK cell function. The NKG2 gene family encodes type II transmembrane proteins with C-type lectin domains, located within the NK complex region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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