Thermo Fisher Scientific LDOC1 Monoclonal Antibody (OTI1A2), TrueMAB
인간 LDOC1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 최적화됨. 동결건조 형태로 제공되며, PBS 완충액에 8% 트레할로스 포함. 암 억제 유전자 연구 및 NF-κB 전사 조절 연구에 유용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Full length human recombinant protein of human LDOC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
LDOC1 contains a leucine zipper-like motif and a proline-rich region similar to an SH3-binding domain.
The protein localizes to the nucleus and is down-regulated in certain cancer cell lines.
It is believed to regulate transcriptional responses mediated by nuclear factor kappa B (NF-κB).
LDOC1 has been proposed as a tumor suppressor gene, potentially playing a role in cancer development and progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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