Thermo Fisher Scientific FGF4 Polyclonal Antibody
FGF4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 동결 건조 형태로 제공되며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human FGF4 (84–97aa RRLYCNVGIGFHLQ) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746372 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family with broad mitogenic and cell survival activities. It plays key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis.
FGF4 is a potent angiogenic factor, expressed in several highly vascularized tumors and in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggest roles in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
FGF4 also regulates neural progenitor proliferation and neuronal differentiation. Recent studies show its growth-promoting role in human embryonic stem cells and a feedback inhibition mechanism by a novel splice isoform that may promote differentiation at later stages.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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