Thermo Fisher Scientific FGF4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.5 µg/mL

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family with broad mitogenic and cell survival activities. It plays key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis.
FGF4 is a potent angiogenic factor, expressed in several highly vascularized tumors and in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggest roles in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
FGF4 also regulates neural progenitor proliferation and neuronal differentiation. Recent studies show its growth-promoting role in human embryonic stem cells and a feedback inhibition mechanism by a novel splice isoform that may promote differentiation at later stages.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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