Thermo Fisher Scientific RhoBTB1/RhoBTB2 Polyclonal Antibody
RhoBTB1/RhoBTB2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 52–98 of human RhoBTB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553474 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 83 kDa.
Purity is >95% by SDS-PAGE.
Target Information
RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases. Members of this subfamily are evolutionarily conserved and characterized by a proline-rich region, a GTPase domain, and two tandem BTB repeats.
RHOBTB1 is highly expressed in placenta, stomach, testis, kidney, and skeletal muscle, whereas RHOBTB3 is abundant in neural and cardiac tissues. RHOBTB1 may play a role in GTPase-mediated signaling and actin filament organization. Decreased expression of RHOBTB1 in head and neck carcinomas suggests its potential role as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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