Thermo Fisher Scientific DATF1 Polyclonal Antibody
DATF1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot 및 IHC(Paraffin) 실험에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C~−20°C 보관 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 154–198 of human Dio-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553478 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 244 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus and activates apoptosis during limb development. Programmed cell death plays an important role in determining tissue amount, shape, and digit definition. Dio-1 expression increases upon apoptotic signals and is suppressed by caspase inhibitors and Bcl-2 expression, supporting its role in programmed cell death initiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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