Thermo Fisher Scientific RSK3 Polyclonal Antibody
Thermo Fisher RSK3 Polyclonal Antibody는 인간 및 생쥐에 반응하며 Western blot에 적합합니다. RPS6KA2 단백질을 인식하는 고품질 rabbit IgG 항체로, Affinity chromatography로 정제되어 높은 특이성과 안정성을 제공합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminal region of mouse RPS6KA2 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2181448 |
Product Specific Information
This antibody is predicted to react with bovine, canine, chicken, and rat based on 100% sequence homology.
In Western blot, this antibody is specific for the ~90 kDa RSK2 protein.
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It is believed that RPS6KA2 acts as a signal-transducing intermediate in cellular responses to several growth factors.
It is expressed in many tissues, with higher levels in lung and skeletal muscle.
The p90 ribosomal S6 kinases (RSK1–4) are downstream members of the ERK/MAPK cascade.
Loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may have a tonic regulation on G-protein coupled signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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