Thermo Fisher Scientific Nkx2.1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.25–0.5 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 2.5 µg/mL

Product Specifications

Product Specific Information

Positive controls that may be used include:

• Human Lung Tissue Lysate
• Human Lung Tissue Slide

Target Information

This gene encodes a protein initially identified as a thyroid-specific transcription factor.
The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes, but has also been shown to regulate the expression of genes involved in morphogenesis.
Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer.
Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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