Thermo Fisher Scientific Tetanus Toxic Fragment C Polyclonal Antibody
테타누스 톡신 C-프래그먼트에 특이적인 토끼 폴리클로날 항체로, Western blot, ELISA, IP에 사용 가능. 높은 농도(68 mg/mL)의 액상 형태로 제공되며, -20°C 보관 권장. 연구용으로만 사용.
- 카탈로그번호
- 100-401-894x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Tetanus Toxic Fragment C Polyclonal Antibody
Thermo Fisher Scientific Tetanus Toxic Fragment C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:40,000 |
| ELISA | 1:50,000–1:250,000 |
| Immunoprecipitation (IP) | 1:1,000–1:40,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bacteria |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Prepared from whole rabbit serum produced by repeated immunizations with a polyhistidine-tagged TTFC fusion protein expressed in E. coli corresponding to full length TTFC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 68 mg/mL |
| Storage Buffer | 0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This antibody is directed against the C fragment of Tetanus toxin derived from Clostridium tetani. A BLAST analysis suggests cross-reactivity with Clostridium tetani. Cross-reactivity with TTFC from other sources has not been determined.
Target Information
Tetanus toxin C-fragment (TTc) is a non-toxic 52 kDa polypeptide generated by papain cleavage of tetanus toxin, corresponding to the C-terminal 451 amino acids.
Tetanus is caused by a neurotoxin produced by the anaerobic bacterium Clostridium tetani, commonly found in soil, feces, and on objects such as rusty metal. Puncture wounds are a common cause of infection.
The toxin acts on presynaptic membranes of both central and peripheral nervous systems to block neurotransmitter release. In its toxic form, tetanus neurotoxin is a 150 kDa protein consisting of a light chain and a heavy chain.
- Light chain: enzymatic portion responsible for toxic effects
- Heavy chain: binds to neuron and aids delivery of light chain
A single disulfide bond links the two chains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.