Thermo Fisher Scientific MRPS30 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal 항체로 Western Blot, ICC/IF, IP에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 순도 95% 이상. PBS/glycerol buffer에 보관하며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human MRPS30 (UniProt ID: Q9NP92-1, amino acids 1–439) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720563 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both composed of multiple mitochondrial ribosomal proteins (MRPs) encoded by nuclear genes essential for mitochondrial protein synthesis.
MRP-S30 (mitochondrial ribosomal protein S30), also known as PDCD9 (programmed cell death protein 9), is a 439 amino acid protein localized in the mitochondrion as a component of the 28S ribosomal subunit. It functions with other MRPs to mediate protein synthesis and is expressed in kidney, liver, heart, and skeletal muscle.
The gene encoding MRP-S30 maps to human chromosome 5, which spans approximately 181 million base pairs and constitutes nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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