Thermo Fisher Scientific JMJD2B Polyclonal Antibody
JMJD2B 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용 히스톤 탈메틸화 효소 분석에 활용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 917–1031 of human KDM4B/JMJD2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720558 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a role in the histone code.
Does not demethylate histone H3 Lys-4, H3 Lys-27, H3 Lys-36, nor H4 Lys-20.
Only able to demethylate trimethylated H3 Lys-9, with weaker activity than KDM4A, KDM4C, and KDM4D.
Demethylation of Lys residue generates formaldehyde and succinate.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-76831_JMJD2B_O94953-1_Rabbit.svg
- PA5-76831_JMJD2B_O94953-1_Rabbit_PDP.jpeg
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