Thermo Fisher Scientific PVRL1/NECTIN1 Recombinant Rabbit Monoclonal Antibody (BLR284L)
PVRL1/NECTIN1 단백질을 인식하는 재조합 토끼 단일클론 항체. Western blot에 최적화되어 있으며, 인간 및 생쥐 시료에 반응. 고순도 정제된 액상 형태로 안정적이며, 세포 간 접착 및 바이러스 수용체 연구에 적합.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR284L |
| Immunogen | Peptide representing a region between residue 200 and 250 of Human Nectin-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells. It is a calcium-independent cell-cell adhesion molecule of the immunoglobulin superfamily with three extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. The protein serves as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells. Mutations in this gene are associated with cleft lip and palate/ectodermal dysplasia 1 syndrome, as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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