Thermo Fisher Scientific PVRL1/NECTIN1 Recombinant Rabbit Monoclonal Antibody (BLR284L)

Applications

• Western Blot (WB): Tested dilution 1:1,000

Product Specifications

Target Information

This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells. It is a calcium-independent cell-cell adhesion molecule of the immunoglobulin superfamily with three extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. The protein serves as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells. Mutations in this gene are associated with cleft lip and palate/ectodermal dysplasia 1 syndrome, as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.